Q-REstrain® Therapy

At Mary-Beth Charno, NP, PLLC Integrative Medicine, we offer advanced, personalized therapies designed to support patients dealing with complex and persistent infections.

Q-REstrain® is a targeted, laboratory-guided therapy developed by RGCC that works with your own immune system to help address chronic viral and bacterial burdens.


What is Q-REstrain®?

Q-REstrain® is an innovative therapy based on a technology known as Supportive Oligonucleotide Technique (SOT). This approach was originally studied in cancer research and has been adapted to support the treatment of chronic infections.

It works by helping your body more precisely recognize and respond to infections that may be contributing to ongoing symptoms.


How It Works

Q-REstrain® works at the level of microbial genetics:

  • Bacteria and viruses rely on genetic material (DNA or RNA) to survive and replicate

  • A highly specific, lab-designed RNA sequence (called an oligonucleotide) is created to match the targeted organism

  • This sequence binds to the organism’s genetic material

  • Once bound, it interferes with the organism’s ability to produce essential proteins

In simple terms:
It helps slow or stop the ability of microbes to replicate, allowing your immune system to regain control.

This is often described as a precision or “lock-and-key” approach, targeting specific organisms without broadly affecting the rest of the body.


Why This Approach Matters

Chronic infections are often difficult to fully resolve because:

  • Microbes may persist long-term in the body

  • They can evade or outlast conventional therapies

  • Some hide within cells or protective biofilms

Q-REstrain® is designed to:

  • Reduce microbial activity at its source

  • Lower overall infectious burden

  • Support more effective immune system function

The goal is not just eradication, but restoring balance between the body and the infection.


Who May Benefit

Q-REstrain® may be considered for individuals experiencing:

  • Chronic Lyme and tick-borne illness

  • Persistent viral infections (such as EBV or HSV reactivation)

  • Post-infectious fatigue or neurologic symptoms

  • Complex, multi-system illness with suspected infectious drivers


What to Expect

The process typically includes:

  • Initial consultation and clinical assessment

  • Blood draw

  • Laboratory processing and custom design (several weeks)

  • In-office IV infusion

  • Ongoing follow-up and monitoring

The infusion is generally well tolerated and performed in a comfortable, supervised setting.


Potential Benefits

  • Supports more precise immune system targeting

  • May reduce symptoms such as fatigue, brain fog, and pain

  • Can complement antimicrobial and integrative therapies

  • May help in cases where progress has plateaued

Individual responses vary.


Safety & Considerations

  • Some patients experience mild fatigue or flu-like symptoms

  • Temporary symptom flares may occur as part of immune activation

  • Q-REstrain® is not FDA-approved as a drug

  • Best used as part of a comprehensive, integrative care plan


Our Integrative Approach

We incorporate Q-REstrain® into a broader care model that may include:

  • IV nutrient therapy

  • Ozone therapy

  • Hormonal and metabolic optimization

  • Gut and immune system support

Our goal is to address both the infection and the terrain in which it exists, supporting long-term healing.


Interested in Q-REstrain®?

We’re happy to help you determine if this therapy is appropriate for your case.

Schedule a consultation or request a complimentary meet-and-greet call to learn more.

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